The National Academies of Sciences, Engineering, and Medicine (NASEM) will convene a national summit that will highlight how racism operates at different levels in science, technology, engineering, math, and medicine (STEMM) settings; identify policies and practices for confronting systemic racism; and identify ways to advance diversity, equity, and inclusion in STEMM settings. Particular attention will be paid to the effect of systemic racism on the careers of individuals belonging to racial and ethnic groups historically underrepresented in the STEMM workforce. These groups include Black/African American, Hispanic/LatinX, American Indian, Alaska Native, Asian, and Pacific Islander communities.